Antiphospholipid antibody in localised scleroderma

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Antiubiquitin antibody in localised and systemic scleroderma.

OBJECTIVE To determine the presence of antiubiquitin antibody (AUbA) in localised scleroderma and systemic sclerosis, as it is frequently found in the sera of patients with systemic lupus erythematosus (SLE) and has also been shown to have a close relationship with antihistone antibodies that have an important role in scleroderma. METHODS Serum samples from patients with localised scleroderma...

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Antiphospholipid Antibodies and Systemic Scleroderma

OBJECTIVE Antiphospholipid antibodies (APLs) could be associated with an increased risk of vascular pathologies in systemic scleroderma. The aim of our study was to search for APLs in patients affected by systemic scleroderma and to evaluate their involvement in the clinical manifestations of this disease. MATERIALS AND METHODS We conducted a cross-sectional descriptive study, from January 20...

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Antiphospholipid Antibodies and Systemic Scleroderma

Dear Editor: We read with great interest the article by Touré and colleagues published in a recent issue of your journal, entitled " Antiphospholipid Antibodies and Systemic Scleroderma ". In this study, they investigated 40 patients with systemic scleroderma (SSc) for the presence of antiphospholipid antibodies (aPLs). Overall, they found aPLs in 23 (57.5%) patients. The most frequently encoun...

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ANTIPHOSPHOLIPID ANTIBODY SYNDROME-A CASE OF AORTIC VALVE INSUFFICIENCY

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The 2006 International Consensus Statement on an Update of the Classification Criteria for Definite Antiphospholipid Syndrome has increased the time between the two laboratory studies required for diagnosis from 6 to 12 weeks. Antibody to beta2 glycoprotein 1 has been included as a criterion. Various non-criteria diagnostic clues such as livedo reticularis, heart valve disease, thrombocytopenia...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2003

ISSN: 0003-4967

DOI: 10.1136/ard.62.8.771